Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Sjogren's hydroxychloroquine 44 Side effects of chloroquine ncbi Inj chloroquine Going off plaquenil All individuals starting Plaquenil treatment should have a baseline ophthalmologic examination within the first year. If the initial ophthalmologic examination is normal and the person is considered low risk, re-testing need not occur for five years. It is recommended that high-risk patients have annual eye examinations. Currently, one of the primary functional screening tests recommended for the evaluation of Plaquenil retinal toxicity is 10-2 white stimulus automated visual fields; however, research shows Asian patients benefited from 24-2 or 30-2 visual fields, given that toxicity often manifests changes beyond the macula in these patients. 9 Because spectral-domain optical coherence tomography SD-OCT is readily accessible and able to detect early structural damage prior to clinical funduscopic findings. Dilated Fundus Exam. The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. There was mild paracentral depigmentation of the RPE in the macula that spared the central fovea OU. The vessels and peripheral exam were normal OU Figure 1. There was no posterior vitreous detachment, retinal tears, or retinal detachments. Ancillary Tests Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil tests Plaquenil Hydroxychloroquine - Side Effects, Dosage., How to Succeed in Plaquenil Screenings Does plaquenil loeer esrSar of chloroquineMechanism of action of hydroxychloroquine in fibromyalgiaCan plaquenil cause thrush Plaquenil” exam on visual field Red on white visual fields Some clinicians may prefer, however more difficult to interpret due to noisemore sensitive, less specific. Re-test for repeatability of defects. PowerPoint. Update on Plaquenil Testing. Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening. Hydroxychloroquine And Chloroquine Screening 2016 AAO.. Feb 19, 2020 A baseline ocular examination is recommended within the first year of starting PLAQUENIL. The baseline exam should include best corrected distance visual acuity BCVA, an automated threshold visual field VF of the central 10 degrees with retesting if an abnormality is noted, and spectral domain ocular coherence tomography SD-OCT. No haven't heard about blood tests for Plaquenil but yes to the eye tests. I've been taking Plaquenil for about 10 years now. But come to think of it I do think the specialist checked my blood early on so maybe if it is going to affect you it is in the early stages of taking it? For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight.