The regular GP is going to put him on steroids to ease the pain. I understand the symptoms of lupus play peeka boo and arent the same in everyone. For the past year ive been extremely tired.has been so bad at times that just getting up to use the restroom is exhausting. I don't work and my husband was unemployed for 2 yrs. Now that he has a job we probably won't qualify, but I will definitely check out this possibility. Pain in lupus can be due to lupus arthritis, or due to pain in muscles and tendons around the joint, or it may be unrelated to lupus. Chloroquine long term side effects How to take plaquenil Can i drink alcohol taking plaquenil I take Plaquinil daily and I use Ibuprofen as needed. I don't take Ibuprofen everyday, but I don't shy away from it when I need it. I wasn't aware that you couldn't take the two together. I think a good place to go for drug information is your pharmacist. My daughter teaches Pharmacy students at Drake University and I'm going to ask her about it. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Summary There is no drug interactions reported by people who take Plaquenil and Ibuprofen and diphenhydramine hydrochloride together yet. This review analyzes the effectiveness and drug interactions between Plaquenil and Ibuprofen and diphenhydramine hydrochloride. If the patient does not respond to these or NSAIDS are contraindicated for some reason then low doses of glucocorticoids such as prednisone are used. I feel guilty considering we now have an income, but on the edge of bankruptcy... The mainstay of treatment in lupus arthritis are NSAIDS, such as naproxen or ibuprofen. Can you take ibuprofen with plaquenil Naproxen and Ibuprofen – Can I Take Both Together, Plaquenil Uses, Dosage & Side Effects - Chloroquine mode of action Motrin ibuprofen interacts with more than 200 other drugs. Plaquenil hydroxychloroquine interacts with more than 100 other drugs. Interactions between your selected drugs and food No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist. Is it safe to take motrin and plaquenil together?. Plaquenil and Ibuprofen and diphenhydramine hydrochloride drug.. Hydroxychloroquine Uses, Dosage & Side Effects -. Ibuprofen Advil, Motrin, an NSAID and Plavix clopidogrel, an antiplatelet, are drugs that thin the blood. Ibuprofen and Plavix should not be taken together because it increases the risk of excessive blood thinning, which may cause gastrointestinal GI bleeding. Ibuprofen and Plavix both have similar side effects like diarrhea, headaches, dizziness, nausea, heartburn, and constipation. I have been on plaquenil for 2 months and waiting for it to work which may take up to 6 months. I have only had weight gain from it. I was on prednisone 10 mg along with plaquenil and had a severe flare up this past weekend. good luck and plaquenil is one of the lowest side effect drugs you can take. I will keep you posted on my RA soon! Good luck! It's not safe to take Ibuprofen while on Prednisone. Taking Ibuprofen together with Prednisone may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and perforation. You should take these medications with food or proton pump inhibitors like Omeprazole to lessen the risk. Your doctor may.