Chloroquine route of administration

Discussion in 'Canadian Pharmaceuticals Online' started by solomon, 29-Feb-2020.

  1. mirumir Guest

    Chloroquine route of administration


    Controlled studies in pregnant women show no evidence of fetal risk. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Animal studies show risk and human studies not available or neither animal nor human studies done. Contact the applicable plan provider for the most current information. D: Use in LIFE-THREATENING emergencies when no safer drug available.

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    Individuals often report with greater depth of itching each time they use the sulphate preparation. Some people often report itching to the tablets without itching to the injectable formulation. This means chloroquine that the intensity of chloroquine itching could also be lowered by altering the route and type of administration as earlier advised. Chloroquine, synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be Chloroquine belongs to a class of drugs known as antimalarials. The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment.

    Active against erythrocytic forms of Plasmodium vivax & P. malariae and most strains of Plasmodium falciparum Precise mechanism not known Bioavailability: ~89% Peak plasma time: 1-2 hr Distributed widely in body tissues (eg, eyes, heart, kidneys, liver, lungs) where retention prolonged; crosses placenta; enters breast milk Partially in liver Half-life: 3-5 days Excretion: urine (~70% as unchanged drug); acidification of urine increases elimination Small amounts may be present in urine months following discontinuation of therapy The above information is provided for general informational and educational purposes only.

    Chloroquine route of administration

    [email protected] FDA-Approved Drugs - Food and Drug Administration, Chloroquine drug Britannica

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  7. Antacids and kaolin can reduce absorption of chloroquine. Administration of this drug and these agents should be separated by at least 4 hours. Cimetidine can block the breakdown of chloroquine, increasing its blood levels. This combination should be avoided. Chloroquine significantly reduces blood levels of ampicillin. Ingestion of ampicillin and chloroquine should be separated by at least two hours.

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    Parenteral administration. Parenteral administration of chloroquine should be considered when there is no expectation of resistance, when the patient is unable to take drugs orally and when neither quinine nor quinidine is available. Chloroquine should not be used in association with gold salts or phenylbutazone. Routes of entry Oral Oral absorption is the most frequent cause of intoxication. Parenteral Intoxication after parenteral administration is rare. A fatal outcome reported was after 250 mg IV chloroquine in a 42-year-old man. ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug.

     
  8. alendi Well-Known Member

    A variety of pharmacologic agents can cause toxicity to the retina. ICD-10-CM Diagnosis Code H35.52 Pigmentary retinal. Retinal Physician - Hydroxychloroquine Maculopathy An. Retinal Pigment Epithelial Mottling Causes & Reasons.
     
  9. axm New Member

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Phosphate Indications, Pharmacology, Dosage. Chloroquine Uses, Side Effects & Warnings - Chloroquine Phosphate - WebMD
     
  10. project2 User

    Chloroquine Oral Route Proper Use - Mayo Clinic Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor.

    Drug Resistance in the Malaria-Endemic World