However, he was quickly contradicted by FDA officials who clarified that more research needs to be conducted before the drug is made available to patients. Hydroxychloroquine—a common derivative of the closely-related drug chloroquine—is used to treat malaria, rheumatoid arthritis and lupus. Plaquenil and mastocytosis Tingling arms plaquenil IL-6 is also produced by synovial and endothelial cells leading to local production of IL-6 in joints affected by inflammatory processes such as rheumatoid arthritis. Dosage When used in combination with DMARDs or as monotherapy the recommended starting dose is 4 mg/kg followed by an increase to 8 mg/kg based on clinical response To treat malaria Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take this medicine for the full prescribed. Dosage for rheumatoid arthritis Adult dosage ages 18 years and older Typical starting dosage 400–600 mg per day, given as a single daily dose or in two 2 divided doses. Hydroxychloroquine and chloroquine are among those touted by some experts as being the most promising."A drug called chloroquine, and some people would add to it hydroxychloroquine... As the COVID-19 pandemic spreads around the world, scientists are scrambling to identify treatments that may be effective against the disease. Hydroxy chloroquine dosage for rheumatoid arthritis Hydroxychloroquine Plaquenil, Hydroxychloroquine - Side Effects, Dosage, Interactions. Hydroxychloroquine discoid lupus Benefits Hydroxychloroquine is a relatively safe medicine that is used to treat mild rheumatoid arthritis. It is also used for complications of lupus. Risks Hydroxychloroquine has few side effects, but nausea and diarrhea may occur when you first start taking the drug. In very rare cases, vision loss has happened. DMARDs Arthritis Foundation. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil Dosage Guide -. The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Systemic lupus erythematosus is treated with 400 mg once or twice daily for several weeks then 200-400 mg daily. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset. The recommended hydroxychloroquine dosage for rheumatoid arthritis is 400 mg to 600 mg a day by mouth as a single dose or divided into two separate doses. However, once a good response is being maintained with hydroxychloroquine, doses may be reduced to 200 mg to 400 mg per day for maintenance. President Donald Trump announced Thursday that the Food and Drug Administration FDA has approved the common malarial drug hydroxychloroquine for the treatment of COVID-19. However, he was.