This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil visual field Trialnet hydroxychloroquine Proguanil is an Antimalarial. The mechanism of action of proguanil is as a Dihydrofolate Reductase Inhibitor. Proguanil is a biguanide derivative which is active against several protozoal species and is used in combination with atovaquone and chloroquine for the prevention and therapy of malaria. There are certain destinations where Chloroquine/Proguanil tablets can offer sufficient protection, but most travellers visiting a malaria zone will require a different antimalarial. Who can obtain Chloroquine/Proguanil without a prescription? There are no specific restrictions on who can buy Chloroquine/Proguanil over the counter. Aug 25, 2016 Proguanil is therefore a valuable drug for causal prophylaxis in falciparum malaria. Avloclor. The mode of action of chloroquine on plasmodia has not been fully elucidated. Chloroquine binds to and alters the properties of DNA. Chloroquine also binds to ferriprotoporphyrin IX and this leads to lysis of the plasmodial membrane. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine and proguanil tablets Chloroquine and Proguanil - Superdrug Health Clinic, Anti-Malaria Tablets Without A Prescription LloydsPharmacy Hydroxychloroquine toxicity eye wikiHydroxychloroquine visionHow to stop diarrhea caused by hydroxychloroquine It is preferable to avoid crushing tablets; however, chloroquine, proguanil, mefloquine and atovaquone/proguanil tablets may be crushed and mixed with jam, honey, pasteurised yoghurt or similar for ease of administration to young children. Tablets may be cut using tablet cutters where necessary. Proguanil and Chloroquine - NPA NPA. Paludrine/Avloclor Anti-Malarial Travel Pack Chloroquine.. Chloroquine and Proguanil Liverpool School of Malaria Prophylaxis.. This medicine contains two types of tablets, Proguanil Hydrochloride and Chloroquine Phosphate. Both these tablets belong to a group of medicines called anti-malarials. It can be used when you travel to some parts of the world to prevent you from getting malaria. What Chloroquine & Proguanil Anti-Malarial Tablets look like and contents of the pack. Proguanil tablets are white and round. They have a break line on one side with the letter ‘P’ on either side of the line. Chloroquine tablets are white and round. They have a break line on one side and the letter ‘A’ either side of the line. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite.