Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil side effects dry skin Chloroquine is a What is hydroxychloroquine Common Plaquenil side effects - a study from FDA data Summary In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. What are some other side effects of Plaquenil? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Not hungry. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Bad side effects of plaquenil Common and Rare Side Effects for Plaquenil Oral, Plaquenil Indications, Side Effects, Warnings - Osteoarthritis joint nodules hydroxychloroquinePlaquenil causes nauseaChloroquine mechanism of action in rheumatoid arthritisChloroquine treatment and virus infection Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Plaquenil oral Reviews and User Ratings Effectiveness, Ease.. The Risk of Retinal Toxicity with Plaquenil. Plaquenil Side Effects - GoodRx. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or. Lower back or side pain noisy breathing painful or difficult urination red irritated eyes red skin lesions, often with a purple center severe mood or mental changes sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stomach pain swelling of the feet or lower legs swollen or painful glands Bad Side Effects of Plaquenil. I have been recently diagnosed with Lupus about 4 months ago and have started plaquenil with the hope it would relieve my symptoms no energy, achy body and severe hair loss. It seems as though it has helped the first two symptoms, but I have horrible constipation.