Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Chloroquine cyanosis What are the side effects of the drug hydroxychloroquine Chloroquine is active against the erythrocytic stages of all species of malaria, and it is also active against the gametocytes of P. vivax, P. malariae, and P. ovale. It is a diprotic weak base, and it works by concentrating in the parasite food vacuole and binding tightly to hematin as it is formed during the digestion of hemoglobin by the. Chloroquine Phosphate Tablets are an antimalarial and amebicidal drug. Each tablet, for oral administration, contains 250 mg chloroquine phosphate equivalent to 150 mg base or 500 mg chloroquine phosphate equivalent to 300 mg base. its effect is believed to result, at least in part from its interaction with DNA. However, the mechanism. Plasmodium falciparum gametocytes the effect of chloroquine on their development M. E. SMALLEY Medical Research Council Laboratories, Fajara, P. O. Box 273 Banjul, The Gambia, West Africa Summary Asexual erythrocytic parasites of Plasmodium falci- parum are killed by chloroquine, whilst mature gametocytes are not. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine effect on gametocytes The effects of subcurative doses of chloroquine on Plasmodium., CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG Chloroquine and cancer However, this effect was most likely the result of a reduction in infectivity in untreated infections, caused by immune activity which was not so pronounced in chloroquine-treated infections. Gametocytaemia gametocytes per r.b.c. showed a strong positive and linear relationship with infectivity. The effect of chloroquine treatment on the infectivity of.. Plasmodium falciparum gametocytes the effect of chloroquine.. Chloroquine confirmed as anti-viral drug for Coronavirus. Chloroquine has been replaced by hydroxychloroquine as an antiinflammatory agent in rheumatic diseases, and these are unapproved, off-label uses. Chloroquine side effects. Common side effects of chloroquine include headache, blurred vision, anorexia, nausea, diarrhea, skin rash and itching. Mefloquine Chloroquine is not active against the gametocytes and the exoerythrocytic forms including the hypnozoite stage P. vivax and P. ovale of the Plasmodium parasites. In vitro studies with Chloroquine demonstrated that it is active against the trophozoites of Entamoeba histolytica. The short-term enhancing effect of chloroquine on gametocyte infectivity was investigated with Plasmodium chabaudi chabaudi, a synchronous parasite which is highly sensitive to chloroquine.