In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil immunosuppressant side effects Plaquenil visualf iedl Aug 26, 2016 In summary Plaquenil isn't causing tyour new problems. It probably caused only the nausea, diarrhea, stomach cramps, and intense vertigo. BTW 100 mg daily may reduce side effects, but this low dosage also greatly annihilates its positive effects. 100 mg are a drop maybe two. on a hot stone. And finally What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Most people do not experience side effects from taking Plaquenil. Among those who do, common side effects include nausea, stomach cramps, dizziness, headaches, and diarrhea. These side effects often decrease over time. Plaquenil can cause serious eye problems, especially if taken at high doses or for longer than five years. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Is gastrointestinal problems common from plaquenil Gastrointestinal involvement in systemic lupus erythematosus., Ask the Expert Plaquenil and Sjögren’s Hydroxychloroquine mechanism of action lupusSide effects of malaria pills chloroquinePlaquenil drug categoryHydroxychloroquine sulfate vs plaquenilPlaquenil saliva Here's a rundown of the latest medical wisdom on eight common gastrointestinal problems. Reflux Symptoms of reflux, such as heartburn, are among the most common digestive ills. Common Digestive Problems and How to End Them Wellness.. Plaquenil Hydroxychloroquine MyLupusTeam. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. I had severe nausea and diarrhea when started on Plaquenil 2 X 200mg tabs once daily almost 3yrs ago. As I also have Crohn's Disease and an Ileostomy this was putting me at serious risk. I was told to stop the Plaquenil until my GI symptoms disappeared.